Pseudo-Xanthoma Elasticum

Eruptive xanthoma.

History A two-month-old girl with unremarkable birth history presented with sudden onset of erythematous papules on the limbs and face for one week. There was no systemic upset, and she remained asymptomatic. Her sister had a history of hypertriglyceridaemia under treatment. The patient's other family members enjoyed good physical health and there was no family history of premature coronary hea...

Pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE) is a genetic metabolic disease with autosomal recessive inheritance caused by mutations in the ABCC6 gene. The lack of functional ABCC6 protein leads to ectopic mineralization that is most apparent in the elastic tissues of the skin, eyes and blood vessels. The clinical prevalence of PXE has been estimated at between 1 per 100,000 and 1 per 25,000, with slight fem...

Pseudoxanthoma elasticum

Xanthoma of the Breast

In a series of nine hundred (circa) tumors of the breast in which the preoperative diagnosis was carcinoma, histologic examination showed that in three instances the lesion was a xanthoma. Although the diagnostic error in reference to xanthoma was, therefore, small, the rarity of these tumors and their relation to abnormal lipoid metabolism prompts a discussion of them, as well as of the xantho...

Xanthoma disseminatum: case report.

Xanthoma disseminatum is a rare, benign, non-Langerhans' cell histiocytic disorder of unknown etiology. A case is presented of a 71-year-old man with a three-year history of disseminated symmetric yellowish papules and plaques on the skin of the face, neck, flexor regions, trunk, extremities and oral mucosa, with fatty infiltration of the liver and pancreas, and cardiac complaints. Xanthomatous...